Revised Dec 12, 2002
Office Address:119 Springdale St., St. John's, Nfld. A1C 5B7
Telephone:709-738-3830 (Business) 709-738-3834 (fax)
Email:jamiek@roadrunner.nf.net
Current Position:
Clinical Associate Professor of Psychiatry, MemorialUniversity of Newfoundland
Director of Research, Discipline of Psychiatry, MUN
Staff Psychiatrist, Health Care Corporation of St. John's
Date of Birth:August 18, 1962, Victoria, B.C.
Education:
High School: Prince of Wales Collegiate, St. John's, GradeXI - passed with honors
Premedical: 1979-81 - Attendance at Memorial University, St.John's
Medical: Memorial University of Newfoundland 1983 - BachelorMedical Science 1985 - M.D.
Post‑Graduate: Memorial University of Newfoundland1985-86 - Rotating Internship
Specialty Training: Memorial University of Newfoundland1986-90 - Psychiatry Residency (1989 - 90 Administrative Resident)
Qualifications:
General license in Newfoundland since 1986: license # 4300
Specialist license in Newfoundland since 1990
Royal College of Physicians & Surgeons of Canada -Psychiatry - 1990
LMCC - 1986 # 67871
Specialist license in Nova Scotia 1990 - 91
Specialist license in Prince Edward Island 1999
Committees:
Health Care Corporation of St. John's Medical AdvisoryCommittee 1995 - 1996
Waterford Hospital Inpatient Psychiatric Service Committee(Chair) 1991 - 1996
Waterford Hospital Clinical Records Committee (Chair) 1991 -1993
Waterford Hospital Bed Utilization Committee (Chair) 1991 -1993
Waterford Hospital Clinical Advisory Committee (Chair) 1991- 1996
Waterford Hospital Pharmacy and Therapeutics Committee(Chair) 1990 -1993
Waterford Hospital ECT Committee (Chair) 1990 - 1996
Waterford Hospital Medical Advisory Committee 1990 - 1995
Waterford Hospital Borderline Personality DisorderManagement Committee 1991 - 1992
Waterford Hospital Credentials Committee 1990 - 1995
Waterford Hospital Open Door Subcommittee (chair) - 1991 -1995
Waterford Hospital Executive Management Team 1991 - 1996
MUN Psychiatry Residency Program Committee 1988 - 1999
MUN Faculty of Medicine AIMS Teaching Resource Group on theEffective Practice of medicine 1991 - 1993
MUN Psychiatry Residency Promotion Committee 1988 - 1998
MUN Psychiatry Residency Psychotherapy Subcommittee 1990 -1991; 1992 - present
MUN Psychiatry Teaching coordinator for the WaterfordHospital, 1992 - 1998
MUN Psychiatry Residency Research Director 1999 - present
Waterford Teaching Committee (chair) 1992- 1999
MUN Internship Committee 1985 - 1989
Secretary, MUN Medical Student's Society 1983 - 84
President, Professional Association of Interns and Residentsof Newfoundland (PAIRN) 1986 - 87
Internal Review Team, MUN Discipline of Neurology 1987
Internal Review Team, MUN Discipline of Family Practice 1988
PAIRN Physician Well-Being Committee 1986 - 1989
PAIRN Psychiatry Representative 1986 - 1989
PAIRN NMA Representative 1987 - 1988
Newfoundland Medical Association (NMA) Board of Directors(PAIRN Representative) 1987 - 88
NMA Physicians Assistance Committee 1987 - 89
Newfoundland Psychiatric Association (NPA) Secretary 1988 -90
NPA President 1998 - 2000
NPA Mental Health Act Committee 1990 - present
NPA Finance Committee 1995 - present
Canadian Psychiatric Association (CPA) Board of Directors1988 - 90
CPA Economics and Management Council 1988 - 90
CPA Director - in - Training 1988 - 90
CPA 1989 annual meeting Local Arrangements Committee1988-1989
APPA 1994 Local Arrangements Committee 1993 - 1994
Canadian Association of Interns and Residents (CAIR) Boardof Directors 1986 - 88
Newfoundland and Labrador Department of Health PhysicianManpower Committee 1988 - 90
Gower Street United Church Ministry and Personnel Committee1993 - 1995
Pleasant Manor (Assisted living program) Board of Directors1991 - present
St. John's Hospital Council Research And InnovationCommittee 1993 - 1998
Health Care Corporation of St. John's Mental Health FocusGroup Phase II 1995
Professional Advisory Board, Schizophrenia Society ofNewfoundland and Labrador - 1998 - present
Department of Health antipsychotic review committee - 1998
CPA Council of Provinces 1998 - 2000
CPA Standing Committee on Professional Standards andPractice 2000 - present
Awards:
Centenary of Responsible Government Scholarship 1978, 79
Atlantic Provinces Psychiatric Association (APPA) AnnualMeeting Best Resident's Paper 1988, 1989, 1990
Schizophrenia Society of Newfoundland and Labrador ÒHope inSchizophrenia AwardÓ 1997-2002
Publications, Posters and Papers:
A Holy Condition. Diagnosis, 1987;4(1):125
A Case of Tourette Syndrome Developing During HaloperidolTreatment. Canadian Journal of Psychiatry, 1990;35(3):228-232
A Case of Neuroleptic Malignant Syndrome Presented at APPAmeeting, 1990
Personality as a Predictor of Placebo/ Nocebo Response toMedications. Presented at APPA meeting, 1989
Flushing Reaction Associated With the Interaction of Phenelzineand Clonazepam. Canadian Journal of Psychiatry 1991;36(5):389
Effects of Placebo Washout and Dose in a Comparison ofSertraline and Amitriptyline. Journal of Clinical Psychiatry 1991;52(9):386
More to Waterford Than Meets the Eye. Evening Telegram1991;113(252):A16
Borderline Personality Disorder in Incest Victims. AmericanJournal of Psychiatry 1992;149(9):1278
Frequency of Electroconvulsive Therapy Use at a ProvincialMental Hospital: A Retrospective Study. Canadian Journal Of Psychiatry 1994;39:551-562
Canadian Editor: National Homestudy - "Management ofAnxiety" University of Alberta Continuing Pharmacy Education, March 1993.Canadian Council on Continuing Education in Pharmacy
New Drug For Treating Schizophrenia Must Prove Its Worth, PsychiatristSays. Evening Telegram, 1993; Sept. 1
Clozapine - Associated Neuroleptic Malignant Syndrome: Twonew cases and review of the literature. Annals of Pharmacotherapy1999;33:623-30
Double Standard For Irregularities. (letter regarding MCPaudits) Evening Telegram March 24, 2000
Olanzapine and Weight Gain. Can J Psychiatry 2000Jun;45(5):493
Editor, MUN Psychiatry Research Newsletter. February 2001.
Rapid Tranquilization With Olanzapine in Acute Psychosis: ACase Series. J Clin Psychiatry 2001;62(suppl 2):12-16
Rapid Tranquilization with an Oral Loading Dose ofOlanzapine in Acute Psychosis. Dawe I, Karagianis J, Thakur A and Begin P. Poster Presentation at 56thAnnual Scientific Program, 2001 Annual Meeting, Society of Biological Psychiatry.May 4, 2001.
Re: Neuroleptic Malignant Syndrome Associated WithQuetiapine. Karagianis J, Hogan K, Ledrew K, Phillips L. Can. J. Psychiatry2001 May;46(4):370
Rapid Tranquilization with Loading Dose Olanzapine in Acute Psychosis.Karagianis J, Dawe I, Thakur A and Begin P. Poster Presentation at 7thWorld Congress of Biological Psychiatry, Berlin Germany. July 4, 2001.
Editor, Mental Illness and New Therapeutic Options: PromiseNow and in the Future. Psychiatry Journal Club 2001, Medical Education NetworkCanada Inc.
High Dose Olanzapine and Prolactin Levels. Coauthored withDr. A. Baksh. Poster presented at Canadian Psychiatric Association Meeting,Montreal, November 16, 2001
Rapid Tranquilization: Calming Agitation With Olanzapine inAcute Psychosis. Acute PsychosisCompendium Series: Psychosis and Schizophrenia 1/2002. Helix Communications
A Sideways View. Dr. Jamie Karagianis MUN MED Vol.14, No. 1Winter 2002
Amantadine Induces Weight Loss In Patients Treated WithOlanzapine. Baruch R, Poulin M,
Editor, MUN Psychiatry Research Newsletter, Vol. 2 No. 1,April 2002.
Dose Optimization in Schizophrenia. Dr. James Karagianis.
Quality of Life, Function and Psychosis Severity in CNOMSS. Karagianis J, Balshaw R,Talling D, Love L. Presentedat XII World Congress of Psychiatry, Yokohama, Japan, August 25, 2002.
An Observational Study of Patients withTreatment-Resistant Schizophrenia Switched to Olanzapine, with Dr. KellieLedrew and Daniel Walker. Poster Presentation at European Congress ofNeuropsychiatry, Barcelona, Spain, October 5, 2002
Doctors Getting the Treatment: Advertising Tells Only Partof the Story. (Letter regarding misinformation about doctorsÕ job action) TheEvening Telegram, Vol. 124 No. 189. October 12, 2002.
Speaking engagements and teaching:
Antidepressants: A review and update on new drugs. Presentedto Corner Brook physicians Nov 21, 1991
Depression: Modern Treatment and Diagnosis Presented toGrand Falls physicians June 15, 1992
A course in psychopharmacology for psychologists. WaterfordHospital: 1991 - 1992
Psychology lecture on the Waterford Hospital and MentalIllness, MUN, 1990
CNS Aspects of AIDS - Waterford Hospital April 1, 1992
Substance Abuse and Dependence, MUN School of Pharmacy,December 3, 1991
Depression - New Directions in Treatment Presented toCarbonear physicians May 19, 1993
Frequency of ECT Use at a Provincial Mental Hospital: aRetrospective Study. Presented at annual meeting of Canadian PsychiatricAssociation September 1993 (poster session)
Ditto, presented as a verbal paper at the MUN 25 YearReunion Scientific Day, 1993
ECT : a review for clinical staff at the Waterford Hospital.January 6, 1993
Affective Disorders. Lecture for Pharmacy Students November1992, November 29, 1993
Antidepressants: the Old and the New Presented to St. John'sGeneral Practitioners November 1993
Psychiatry: The Far Side - Presented to St. John's HighSchool Students, Fall 1993
Moderator, Waterford Day in Psychiatry, November 1995
Mental Status Examination - Lecture for MUN nursingstudents, September, 1996
The Psychotic Patient - Lecture for MUN Family Practicedoctors and students, March 1996, March 1997
The Anxious Depressed Patient - Presented to four groups ofrural Newfoundland physicians, April 1998
New developments in treatment of schizophrenia - Presentedto the annual meeting of Canadian Association of Hospital PharmacistsNewfoundland Branch, May 1999
Workshop on second generation antipsychotics - Presented toNewfoundland Psychiatrists, June, 1999
Atypical Antipsychotics - Presented to Grand Fallsphysicians and allied health professionals, April 2000
Treatment and Management of Patients with Psychosis:Improving Quality of Life - Presented to Family Doctors Sept 10, 2000 DundeeResort, Nova Scotia and Sept 17, 2000 White Point Resort, Nova Scotia.
Optimizing Outcomes in the Treatment of Schizophrenia(Moderator and Presenter) Presented to Atlantic Provinces Psychiatrists, QuebecCity, January 27 - 28, 2001.
Schizophrenia Awareness for Health Care Workers. Presentedto Schizophrenia Society of Newfoundland and Labrador in St. John's, February23, 2001.
"Hope Talk" - Where we have come from, where weare now, and where we are hoping to go. Public Address at meeting ofSchizophrenia Society of Newfoundland and Labrador, St. John's, April 25, 2001.
Moderator, Psychiatry Residents Research Day. May 17, 2001,MUN, St. JohnÕs.
Calming the Agitated Patient with Olanzapine.
Comparing Glycemic ProfilesAcross Treatment Options in Psychiatric Disorders, and Rapid Tranquilizationwith Olanzapine. Grand RoundsPresentation to Psychiatrists. St. John,NB. October 12, 2001.
Primary care for patients with behavioural, mood and thoughtdisturbances: focus on olanzapine. Presented to GPs in Lewisporte, Clarenville,Botwood, Grand Falls, Twillingate, NF, October 17, 18, 19, 2001.
Oral Olanzapine in the Acute Setting, and a workshop on theapproach to the agitated psychotic patient. Presented to Psychiatrists fromIreland. Cape Town, South Africa. November 13, 2001.
Atypical Rapid Tranquilization for Acutely Agitated PatientsCapable of Taking an Oral Medication. (Lilly Satellite Symposium) Presented toCanadian Psychiatric Association, Montreal, November 17, 2001.
Oral Treatment in the Acute Setting - Loading DoseExperience with Olanzapine. Presented to psychiatrists in Sweden. Stockholm,November 27, 2001.
Intramuscular Olanzapine in the Acute Setting.
Atypical Rapid Tranquilization with Oral Olanzapine.
Managing the Phases ofSchizophrenia Ð A Matter of Compliance. Presented to Newfoundland Psychiatrists and mental health professionals,St. JohnÕs, March 23, 2002.
Atypical Rapid Tranquilization for Acutely AgitatedPatients. Presented toPsychiatrists and mental health professionals in Hamilton, Brampton,Mississauga, Acton, Oakville and Toronto, April 17-19, 2002.
Management of Behavioural Agitation in the EmergencySetting: New Treatment Options. Presented to emergency physicians at CAEP meeting, Hamilton April 17,2002.
Olanzapine: Oral Rapid Tranquilization and IM for AcutelyAgitated Patients. Presented to Psychiatrists and mental Health Professionalsin Ottawa, Barrie, Belleville, Oshawa, Kingston,Toronto, June 4-7, 2002
Managing the Acutely Disturbed Patient in Psychiatry: TheArt and
Science from Canada. Presented toPsychiatrists in England: London, GantÕs Hill, Chelmsford, and Manchester, June17-20, 2002.
Oral Atypical Antipsychotic Strategies for RapidTranquilization. Presented toPsychiatrists in Harpenden, England, June 19, 2002
Trying to Stop the Revolving Door: The Relapse Prevention Challenge.
Olanzapine: Oral Rapid Tranquilization and IM for AcutelyAgitated Patients. Presented to Psychiatrists and Mental Health Professionalsin Charlottetown, PEI, July 5, 2002
Acute Care Psychiatry: Agitation. Wednesday at Noon Lecture Series. Presented to General Practitioners all over Newfoundland viateleconference, September 25, 2002
Management of BehaviouralAgitation in the Acute Setting. Presented to Psychiatrists and Mental Health Professionals in Calgary,Ponoka and Waterton, Alberta, September 26 - 28
Management of Acute Psychosis with Agitation.
Management of Acute Psychosis with Agitation, Presented toPsychiatrists in Marmaris, Turkey. (Lilly Satellite Symposium) October 24,2002.
Damned If You Do, Damned If You DonÕt: Management ofBorderline Personality Disorder in Crisis While Avoiding Admission.
Managing the phases of schizophrenia - A matter of compliance- focus on olanzapine. Presentedto psychiatrists and mental health professionals in Christchurch, Dunedin,Auckland, Hamilton, Rotorua and Wellington New Zealand.
Novel antipsychotics in schizophrenia and beyond Ð morehope now than ever before. Presented to Newfoundland and Labrador Government Cabinet MinistersDecember 10, 2002.
Media Interviews:
Risperidone. CBC Morning Show, Summer 1993
New Antipsychotic Drugs. Evening Telegram, September 1, 1993
Current Status of ECT, CBC TV The Health Show March 6,7,1996. Broadcast March 14, 1996
Interview regarding ECT "The Shock of the New ECT"published in March 1998 Chatelaine
Interview regarding ECT ÒShock to the SystemÓ published inThe Medical Post, March 10, 1998 By M. Cecelia Cancelliere.
Interviewed by a Journalist at Canadian PsychiatricAssociation Annual General Meeting, November 18, 2001, regarding Olanzapine andProlactin: ÒCPA: High Doses of Olanzapine do notIncrease Prolactin LevelsÓ By Louise Gagnon
Past Research:
Clinical investigator in: A multicenter trial comparing theefficacy and tolerability of paroxetine versus desipramine in outpatients withmajor depression. (Sponsored by SmithKline Beecham)
Is schizophrenia an autoimmune disease? With Dr. WilliamMarshall
Using amantadine or nizatidine to assist in weight loss inpatients treated with olanzapine (with other Canadian investigators
Clinical Investigator in: Canadian National OutcomesMeasurement Study in Schizophrenia (CNOMSS)(Sponsored by Janssen).
An observational study of patients with agitation treatedwith intramuscular medications or Zydis. (Organized by Lilly).
Clinical Investigator in an open label study of acombination of olanzapine and fluoxetine in depression F1D-MC-HGIP (Sponsoredby Lilly).
Current Research:
A naturalistic study of the onset of action of rapidlydissolving olanzapine.
Clinical Investigator in Olanzapine plus Fluoxetine inCombination for Treatment-Resistant Depression without Psychotic Features.H6P-MC-HDAO (Sponsored by Lilly)
Long-term Treatment with Atypical Antipsychotics: Amulticenter retrospective, observational study of atypical antipsychoticprescribing practices and outcomes in outpatients treated with atypicalantipsychotics for at least 1 year. Principal Investigator, with Dr. Barry Jones and Dr. Brian Morris.(Sponsored by Lilly)
Current Memberships:
Newfoundland and Labrador Medical Association
Newfoundland Psychiatric Association (Past President)
Atlantic Provinces Psychiatric Association
Canadian Medical Protective Association # 733539
Canadian Psychiatric Association
Royal College of Physicians and Surgeons of Canada
Employment History:
Retail Sales - footwear 1979
Lifeguard / Pool Maintenance Worker 1977 - 79
Chemistry Lab Demonstrator 1981
Student Research Assistant (chemistry), MUN, 1980 - 81
General Practice Locum (Waterford Hospital), 1987 - 89
Assistant Professor of Psychiatry, M.U.N., 1990 - 91
Psychiatric Locum, Aberdeen Hospital, Nova Scotia, July 1991
Clinical Lecturer, M.U.N., 1991 - 1992
Private Practice in Psychiatry Waterford Hospital andoutpatient clinic 1990 - Present
Clinical Director, Waterford Hospital, 1991 - 1996
Assistant Medical Director, Waterford Hospital 1991 - 1996
Chief of Service, Unit N3B, Waterford Hospital 1995 -1998
Chief of Service, Unit E3A, Waterford Hospital, 1998 -present
Clinical Assistant Professor of Psychiatry, M.U.N., 1992 -Present
Consultant Psychiatrist to the Department of Justice forcourt assessments 1991 - present
Staff Psychiatrist, Waterford Hospital, 1990 - present
Active Staff, Department of Psychiatry, the GeneralHospital, 1994 - present
Active Staff, Department of Psychiatry, St. Clare's MercyHospital, 1994 - present
Staff Psychiatrist, Health Care Corporation of St. John's,1996 - present
Expert Witness Recognition in Psychiatry in Newfoundland andLabrador:
Provincial Court
Unified Family Court
Supreme Court
Hospital Privileges:
Full admission and treatment privileges at WaterfordHospital, the General Hospital and St. Clare's sites, Health Care Corporationof St. John's
On call coverage provided for:
Health Care Corporation of St. John's
St. John's City Lockup
Extra Courses and Training:
Centre for Management Development (Faculty of BusinessAdministration, MUN) courses for Waterford Managers: Conflict Management -September 1991 Authority and Delegation - October 1991
The Physician Manager for Psychiatrists: Managerial Issuesin Mental Health Services - Institute of Health Management, University ofToronto, Spring, 1992
Finance and Accounting for Physician Managers - Institute ofHealth Management, University of Toronto, Fall 1992
Information Systems for Physician Managers - Institute ofHealth Management, University of Toronto, Fall 1992
Total Quality Management - Continuous Quality ImprovementWorkshop - Waterford Hospital, December 1992
Quality Assurance / Risk Management Workshop - WaterfordHospital, December 1992
Academic Interests:
novel antipsychotics
electroconvulsive therapy
borderline personality disorder
treatment-resistant depression
schizophrenia and related psychoses
Leisure time interests:
woodturning and furniture building
guitar
golf
gardening and bonsai
fishing, hunting and camping
computers and the internet
sailing
References:
1. Dr. Howard Strong
Professor of Psychiatry
Faculty of Medicine
Memorial University of Newfoundland
709-777-6717
2. Dr. Angela Penney
Assistant Professor of Psychiatry
Faculty of Medicine
Memorial University of Newfoundland
709-777-7297
3. Dr. Thomas Cantwell
Program Clinical Chief
Mental Health Program
Health Care Corporation of St. John's
709-777-3322